TECHNOLOGY

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•	Exploring donor demographics effects on hepatocyte yield and viability: Results of whole human liver isolation from one center

•	Application of pulsed electric ? elds for the valorization of platelets with no therapeutic value for transfusion medicine

•	The growing role of precision and personalized medicine for cancer treatment

•	Real-time measurement of cholesterol secreted by human hepatocytes using a novel microfluidic assay

•	End-to-end blood testing device demonstrates capacity to draw sample and provide diagnostic results at the point-of-care

•	A scale-up nanoporous membrane centrifuge for reverse osmosis desalination without fouling

•	A photocrosslinkable, thermoreversible, type-I collagen bioink for photolithographic printing of 3D scaffolds

•	A novel model for ex situ reperfusion of the human liver following subnormothermic machine perfusion

•	University of Minnesota researchers report novel in silica platform for investigating quiescence in dormancy-capable cancer cells

•	Rapid antibiotic sensitivity test using microfabricated microwell arrays

•	Paper pumps power portable microfl uidics, biomedical devices

•	Continuous-flow, electrically-triggered, single cell-level electroporation

•	A cost-effective micromilling platform for rapid prototyping of microdevices

•	Image-based modeling: A novel tool for realistic simulations of artificial bone cultures

•	Responsive filtration membranes by polymer self-assembly

•	A three-dimensional paper-based microbial fuel cell operating under continuous flow condition

•	Electropermanent magnet actuation for droplet ferromicrofluidics

•	A computational model was developed to simulate the long term effects of cardiac regenerative therapies in a left ventricle

•	An all-on-chip method for testing neutrophil chemotaxis induced by fMLP and COPD patient's sputum

•	Two-stage nanoparticle delivery of piperlongumine and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) anti-cancer therapy

•	Silica nanoparticles deliver siRNAs through novel endocytosis pathway, resulting in effi cient silencing without cytotoxicity

•	Rapid generation of collagen-based microtissues to study cell-matrix interactions

•	Signal transduction of the physical environment in the neural differentiation of stem cells

•	Extensive review of key contributions to understanding the mechanics of the urinary bladder with a focus on material testing and theoretical modeling

•	A hybrid neural interface optrode with a polycrystalline diamond heat spreader for optogenetics

•	Engineered monomeric streptavidin for cell labeling and proximity dependent biotinylation

•	Versatile microfl uidic platform provides quantitative assessment of dynamic deformability and adhesion of red blood cells

•	Collagen and heparan sulfate coatings differentially alter cell proliferation and attachment in vitro and in vivo

•	High-throughput evaluation of synthetic metabolic pathways

•	Study reports liquid salts deliver drugs through the skin with enhanced effi cacy and reduced toxicity

•	Phase morphology of segmental polyurethanes provides signals for endothelial cells to organize into networks

•	A microfluidic biochip for blood cell counts at the point-of-care

•	Micro photosynthetic power cells may be the green energy fount for next generation

•	Pneumothorax treatment gets less painful

•	Pre-purifi cation system allows heightened purity of a metal binding compound

•	A novel technology to produce microalgae biomass as feedstock for biofuel, food, feed and more

•	The consortium of motile and cellulose degrading bacteria can be used for Solid State cellulose hydrolysis

•	Process concept for a zero-emission route to clean middle-distillate fuels from coal

•	Perspectives on using pulse electric fi eld to enhance biogas yield in anaerobic digestion

•	BioLEGO - A web-based application for biorefi nery design and evaluation of serial biomass fermentation

•	Scaffold-integrated microchips for end-to-end in vitro tumor cell attachment and xenograft formation

•	Microfabricated device allows evaluation of the efficacy, toxicity of drugs metabolized through the liver

•	Biogas to biomethane upgrading by water absorption column at low pressure and temperature

•	Stain-less staining provides a new tool for clinicians and researchers

•	"Universal" vitrifi cation of cells by ultra-fast cooling

•	Intermittently delivered pulsed electric fi elds technology could replace boiling and refrigeration of milk in the low-income countries

•	Modulating electrolytic tissue ablation with reversible electroporation pulses

•	Fast sorting of CD4+ T cells from whole blood usingglass microbubbles

•	RF heating of magnetic nanoparticles improves the thawing of cryopreserved biomaterials

•	New study shows that yoga and meditation may help train the brain

•	Milestone reached in work to build replacement kidneys in the lab

•	Continuous fabrication system for highly aligned polymer fi lms provides method for tuning mechanical and thermal properties in bulk polymers

•	Stochastic variations of migration speed between cells in clonal populations

•	Accounting for biological aggregation in heating and imaging of magnetic nanoparticles

•	Focal blood-brain-barrier disruption with high-frequency pulsed electric fields

•	A highly sensitive microsphere-based assay for early detection of Type I diabetes

•	Aqueous two-phase systems enable multiplexing of homogeneous immunoassays

•	Inherent magnetic fields can be exploited to measure the positions of ferromagnetic objects accurately without requiring pre-calibration

•	Stopping scar growth and reducing scar tissues with a novel drug-eluting patch

•	Pulsed electrical fields destroy antibiotic-resistant bacteria infecting burn injuries

•	Device isolates most aggressive cancer cells

•	Brain-on-a-chip axonal strain injury model highlights mitochondrial membrane potential threshold and assesses potential new therapeutic

•	Nanoparticle "barcodes" can be painted onto tissues to enable the rapid diagnostic imaging of multiple cancer-related biomarkers

•	Chemically- and mechanically-tunable porated polyethylene glycol gels for leukocyte integrin independent and dependent chemotaxis

•	An ultrathin collagen matrix biomaterial tool for 3-D microtissue engineering

•	Tiny biomolecular tweezers facilitate study of mechanical force effects on cells and proteins

•	Diffeomorphometry and Geodesic Positioning Systems for human anatomy

•	A pocket-size ultrasonic nebulizer employing a novel silicon-based megahertz (MHz) multiple-Fourier horn nozzle produces monodisperse aerosols for improved inhaled drug delivery

•	Design and development of a force sensing skin adapted to a child surrogate to identify potential bruising locations

•	Combining cryoablation and nanoparticle-encapsulated anticancer drug is effective in destroying cancer stemlike cells

•	Structural insights into the inner workings of a viral nanomachine

•	Enhancing the immune response through next generation polymeric vaccine adjuvants

•	High voltage, short pulsed electric fields hold promise to reveal the enigma of scars and to induce scarless tissue regeneration

•	UCF researchers develop breakthrough in neuromuscular junction studies

•	Multimodal tracking of cell dynamics over months gives microscopic view of complex processes in skin regeneration

•	Simple, non-invasive eye test can replace skin biopsy for diagnosing small nerve fiber loss and evaluating the efficacy of therapeutics

•	Microfluidic platform enables measurement of neutrophil directional migration from a droplet of blood

•	Graphene: a promising new material for electrochemical sensor technology

•	Modifications to a recombinant Mullerian inhibiting substance brings this new biological therapeutic one step closer to clinical testing in ovarian cancer patients

•	Full automated venipuncture device can improve pediatric experience

•	Target DNA detection and quantitation on a single cell with single base resolution

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Technology